Ischemic Heart Disease and Liver Cirrhosis: Adding Insult to Injury.
Irina GîrleanuAnca Victorița TrifanLaura HuibanCristina Maria MuzicaOana Cristina PetreaAna-Maria SingeapCamelia CojocariuStefan ChiriacTudor CuciureanuIrina Iuliana CostacheCarol StanciuPublished in: Life (Basel, Switzerland) (2022)
The link between heart and liver cirrhosis was recognized decades ago, although much data regarding atherosclerosis and ischemic heart disease are still missing. Ischemic heart disease or coronary artery disease (CAD) and liver cirrhosis could be associated with characteristic epidemiological and pathophysiological features. This connection determines increased rates of morbidity and all-cause mortality in patients with liver cirrhosis. In the era of a metabolic syndrome and non-alcoholic fatty liver disease pandemic, primary prevention and early diagnosis of coronary artery disease could improve the prognosis of liver cirrhosis patients. This review outlines a summary of the literature regarding prevalence, risk assessment and medical and interventional treatment options in this particular population. A collaborative heart-liver team-based approach is imperative for critical management decisions for patients with CAD and liver cirrhosis.
Keyphrases
- coronary artery disease
- metabolic syndrome
- risk assessment
- percutaneous coronary intervention
- end stage renal disease
- cardiovascular events
- coronary artery bypass grafting
- newly diagnosed
- heart failure
- chronic kidney disease
- ejection fraction
- healthcare
- cardiovascular disease
- coronavirus disease
- atrial fibrillation
- risk factors
- palliative care
- aortic stenosis
- heavy metals
- adipose tissue
- insulin resistance
- acute coronary syndrome
- left ventricular
- liver fibrosis
- uric acid