Basal FSH values are positively associated with aneuploidy incidence in pre-advanced maternal age (AMA) but not in AMA patients.
Catherine K JacobsMariana NicolieloJosé Roberto AlegrettiMariabeatrice Dal CantoMario Mignini RenziniElena De PontiMauricio Barbour ChehinEduardo L A MottaAline R LorenzonJose BuratiniPublished in: Journal of assisted reproduction and genetics (2024)
Maternal basal FSH values are associated with embryo aneuploidy in pre-AMA but not in AMA patients. The present findings suggest that basal FSH is a useful parameter to assess aneuploidy risk in pre-AMA patients and reinforce the hypothesis that excessive FSH signalling can predispose to oocyte meiotic errors.