N-Acetyl-l-Cysteine Supplement in Early Life or Adulthood Reduces Progression of Diabetes in Nonobese Diabetic Mice.
Lital Argaev FrenkelHava RozenfeldKonstantin RozenbergSanford R SampsonTovit RosenzweigPublished in: Current developments in nutrition (2018)
NAC decreased morbidity of NOD mice by attenuating the immune response, presumably by eliminating oxidative stress, and might be beneficial in reducing morbidity rates of T1D in high-risk individuals.
Keyphrases
- early life
- immune response
- oxidative stress
- type diabetes
- transcription factor
- cardiovascular disease
- high fat diet induced
- dna damage
- diabetic rats
- living cells
- ischemia reperfusion injury
- depressive symptoms
- fluorescent probe
- adipose tissue
- metabolic syndrome
- inflammatory response
- genome wide analysis
- skeletal muscle
- wild type
- weight loss
- heat shock