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Ruthenium(II) complexes as bioorthogonal two-photon photosensitizers for tumour-specific photodynamic therapy against triple-negative breast cancer cells.

Mingwei LinShanshan ZouXinxing LiaoYu ChenDiqing LuoLiangnian JiHui Chao
Published in: Chemical communications (Cambridge, England) (2021)
Herein, we developed the first Ru(ii) complex-based bioorthogonal two-photon photosensitizers. Through bioorthogonal labelling, they realize effective tumour-specific photodynamic therapy against triple-negative breast cancer cells.
Keyphrases
  • photodynamic therapy
  • breast cancer cells
  • fluorescence imaging
  • living cells
  • monte carlo
  • quantum dots
  • single molecule