Impact of losing adipose tissue on outcomes from PD-1/PD-L1 inhibitor monotherapy in non-small cell lung cancer.

Naoya NishiokaTateaki NaitoTaichi MiyawakiMichitoshi YabeKosei DoshitaHiroaki KodamaEriko MiyawakiYuko IidaNobuaki MamesayaHaruki KobayashiShota OmoriRyo KoKazushige WakudaAkira OnoHirotsugu KenmotsuHaruyasu MurakamiKoichi TakayamaToshiaki Takahashi

Published in: Thoracic cancer (2022)

This study showed that decreasing adipose tissue without cachexia might favor the therapeutic effects of immunotherapy.

Keyphrases

adipose tissue
insulin resistance
high fat diet
combination therapy
clinical trial
type diabetes
skeletal muscle