Prediction of Free from Total Mycophenolic Acid Concentrations in Stable Renal Transplant Patients: A Population-Based Approach.

Helena ColomFranc AndreuTeun van GelderDennis A HesselinkBrenda C M de WinterOriol BestardJoan TorrasJosep M CruzadoJosep M GrinyóNúria Lloberas

Published in: Clinical pharmacokinetics (2019)

A reliable protein-binding population PK model was developed for prediction of fMPA or tMPA from each other and for dose guiding in stable renal transplant recipients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
binding protein
small molecule
protein protein
amino acid
dna binding