Monitoring of Dynamic Changes and Clonal Evolution in Circulating Tumor DNA From Patients With IDH -Mutated Cholangiocarcinoma Treated With Isocitrate Dehydrogenase Inhibitors.
Morten LapinHelen J HuangSharmeen ChaganiMilind M JavleRachna T ShroffShubham PantMohamed A GoudaAnjali RainaKiran MadwaniVeronica R HolleyS Greg CallDerek J DustinRichard B LanmanFunda Meric-BernstamVictoria M RaymondLawrence N KwongFilip JankuPublished in: JCO precision oncology (2022)
mutations in ctDNA in patients with advanced cholangiocarcinoma is feasible, and dynamic changes in ctDNA can correspond with the clinical course and clonal evolution.