TIMP1 and MMP9 are predictors of mortality in septic patients in the emergency department and intensive care unit unlike MMP9/TIMP1 ratio: Multivariate model.

Maria Eugenia NiñoSergio Eduardo SerranoDaniela Camila NiñoDiana Margarita McCoshamMaria Eugenia CardenasVivian Poleth VillarealMarcos LopezAntonio Pazin-FilhoFabian Alberto JaimesFernando CunhaRichard SchulzDiego Torres-Dueñas

Published in: PloS one (2017)

It could be argued that plasma levels of TIMP1 should be considered as a promising prognostic biomarker in the setting of sepsis. Additionally, this study, like other studies with large numbers of septic patients does not support the predictive value of TIMP1 / MMP9.

Keyphrases

intensive care unit
emergency department
end stage renal disease
ejection fraction
newly diagnosed
acute kidney injury
prognostic factors
type diabetes
cardiovascular disease
risk factors
extracorporeal membrane oxygenation