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Characterisation of a Hepatitis C Virus Subtype 2a Cluster in Scottish PWID with a Suboptimal Response to Glecaprevir/Pibrentasvir Treatment.

Rajiv ShahStephen T BarclayErica S PetersRay FoxRory GunsonAmanda Bradley-StewartSamantha J ShepherdAlasdair MacLeanLily TongVera Jannie Elisabeth van VlietMichael Ngan Chiu BongAna FilipeEmma C ThomsonChris Davis
Published in: Viruses (2022)
This study describes a cluster of HCV genotype 2a infection associated with a lower-than-expected SVR rate following GP treatment in association with the NS5A mutations L31M+R353K.
Keyphrases
  • hepatitis c virus
  • human immunodeficiency virus
  • zika virus
  • replacement therapy
  • smoking cessation