Unexpected discovery of small HNF1α-inactivated hepatocellular adenoma in pathological specimens from patients resected for liver tumours.
Charles BalabaudChristophe LaurentBrigitte Le BailClaire CastainLaurent PossentiNora FrulioLaurence ChicheJean Frédéric BlancPaulette Bioulac-SagePublished in: Liver international : official journal of the International Association for the Study of the Liver (2018)
Taken together, H-HCAs are more frequent than we initially supposed as micro and small HCAs cannot all be detected by routine ultrasound. Despite no information on the potential growth of these micro/small H-HCAs, there is no argument to stop oral contraceptives or to ask for a specific regular surveillance. The association of different subtypes of HCAs with focal nodular hyperplasia suggests they share or have common etiological factors.