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Correlation of Different Serum Biomarkers with Prediction of Early Pancreatic Graft Dysfunction Following Simultaneous Pancreas and Kidney Transplantation.

Nora JahnMaria Theresa VoelkerSven LaudiSebastian N StehrStefan SchneebergerGerald BrandacherElisabeth SucherSebastian RademacherDaniel SeehoferRobert SucherHans Michael Hau
Published in: Journal of clinical medicine (2022)
In the current study, the combination of peak lipase and CRP levels were highly effective in predicting early pancreatic graft dysfunction development following SPKT. In contrast, for early renal graft dysfunction the predictive value of this parameter was less sensitive. Intensified monitoring of these parameters may be helpful for identifying patients at a higher risk of pancreatic ischemia reperfusion injury and various IRI- associated postoperative complications leading to ePGD and thus deteriorated outcome.
Keyphrases
  • kidney transplantation
  • oxidative stress
  • ischemia reperfusion injury
  • magnetic resonance
  • magnetic resonance imaging
  • computed tomography
  • contrast enhanced