Meta-analysis of genome-wide association studies and functional assays decipher susceptibility genes for gastric cancer in Chinese populations.

Caiwang YanMeng ZhuYanbing DingMing YangMengyun WangGang LiChuanli RenTongtong HuangWenjun YangBangshun HeMeilin WangFei YuJinchen WangRuoxin ZhangTianpei WangJing NiJiaping ChenYue JiangJuncheng DaiErbao ZhangHongxia MaYanong WangDazhi XuShukui WangYun ChenZe-Kuan XuJianwei ZhouGuozhong JiZhaoming WangZhengdong ZhangZhi-Bin HuQingyi WeiHongbing ShenGuangfu Jin

Published in: Gut (2019)

We identified 12 loci to be associated with GC risk in Chinese populations and deciphered the mechanisms of PRKAA1 at 5p13.1 and NOC3L at 10q23.33 in gastric tumourigenesis.

Keyphrases

genome wide association
systematic review
case control
genome wide
meta analyses
high throughput
genetic diversity
gene expression
transcription factor
gas chromatography
genome wide association study
genome wide analysis