Thrombectomy in M2 occlusion compared to M1 occlusion: treatment effects of Thrombolysis In Cerebral Infarction (TICI) 2b and TICI 3 recanalization on functional outcome.

Helge C Kniep Lukas Meyer Gabriel BroocksTobias D FaizyMatthias BechsteinCaspar BrekenfeldFabian Alexander Flottmann Noel Van Horn Vincent Geest Laurens WinkelmeierAnna AlegianiMilani Deb-ChatterjiUta HanningGoetz ThomallaFiehler JensSusanne Gellissennull null

Published in: Journal of neurointerventional surgery (2023)

Results suggest that successful recanalization with TICI ≥2b versus TICI <2b after MT in M2 occlusions provides significant patient benefit with treatment effects comparable to M1 occlusions. The probability of functional independence increased by 20 percentage points (NNT 5) and stroke-related mRS increase was reduced by 0.9 mRS points. In contrast to M1 occlusions, complete recanalization TICI 3 versus TICI 2b had lower additional beneficial effect.

Keyphrases

middle cerebral artery
magnetic resonance
computed tomography
pulmonary embolism
atrial fibrillation
magnetic resonance imaging
replacement therapy