Genome-wide capture sequencing to detect hepatitis C virus at the end of antiviral therapy.
Peng PengYanjuan XuMichael W FriedAdrian M Di BisceglieXiaofeng FanPublished in: BMC infectious diseases (2020)
Our data provides concept evidence for a highly sensitive HCV detection by capture sequencing. The abundance difference of HCV sequencing reads at the end of HCV antiviral therapy could be applied to predict treatment outcomes.
Keyphrases
- hepatitis c virus
- human immunodeficiency virus
- single cell
- genome wide
- dna methylation
- big data
- stem cells
- loop mediated isothermal amplification
- machine learning
- mesenchymal stem cells
- hiv infected
- real time pcr
- mass spectrometry
- cell therapy
- copy number
- deep learning
- antiretroviral therapy
- replacement therapy
- chemotherapy induced