At-line LC-QTOF-MS micro-fractionation of Derris scandens (Roxb.) Benth, coupled to radioassay for the early identification of PDE5A1 inhibitors.
Samjhana BhandariNitra NuengchamnongNattiya ChaichamnongTongchai SeasongKornkanok IngkaninanPrapapan TemkitthawonPublished in: Phytochemical analysis : PCA (2019)
Our results demonstrated that the at-line coupled LC-QTOF-MS micro-fractionation with PDE5A1 inhibitory assay is a valuable tool for identifying PDE5A1 inhibitors from complex extracts.