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Real-World Outcomes Among Older Mexican Women with Breast Cancer Treated with Neoadjuvant Chemotherapy.

Paula Cabrera-GaleanaEnrique Soto Pérez de CelisNancy Reynoso-NoveronCynthia Villarreal-GarzaFernando Lara-MedinaAlberto Alvarado-MirandaJosé Rodrigo Espinosa-FernandezNereida Esparza-AriasAlejandro MoharJuan Enrique Bargallo-Rocha
Published in: The oncologist (2020)
The majority of older patients with breast cancer in high-income countries present with early-stage disease, leading to a lack of information regarding the use of neoadjuvant chemotherapy in real-world settings. This article reports the outcomes of older Mexican women with breast cancer who received neoadjuvant chemotherapy compared with their younger counterparts. Although older women (particularly those with triple-negative tumors) were less likely to have a pathologic complete response after neoadjuvant treatment, age was not an independent factor for recurrence. Achieving a pathologic complete response was associated with improved survival, regardless of age.
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