Fertility preservation before cancer treatment: the dilemma of saying 'no' as the price of glory.
Michaël GrynbergNathalie SermondadePublished in: Human reproduction (Oxford, England) (2024)
A great deal of work has been carried out by professionals in reproductive medicine in order to raise awareness about fertility preservation (FP) techniques, particularly for women, and to ensure that FP is included in the care of young adults treated for cancer or a pathology requiring gonadotoxic treatment. If the importance of the development of our discipline is obvious, our militancy in favour of FP and our emotional projections must not make us forget that medical thinking must be carried out not only on a case-by-case basis, weighing up the benefit-risk balance, but also without losing sight that conceiving a child with one's own gametes is not a vital issue. The cultural importance given to the genetic link with offspring may bias patients' and physicians' decisions, while other ways of achieving parenthood exist, and are often more effective. Systematic information should be provided on the existence of FP techniques, but this should not lead to their systematic implementation, nor should it obscure that early information will also allow patients to begin projecting themselves in alternative options to become parents.
Keyphrases
- end stage renal disease
- newly diagnosed
- healthcare
- young adults
- ejection fraction
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- mental health
- type diabetes
- squamous cell carcinoma
- gene expression
- patient reported outcomes
- pregnant women
- health information
- quality improvement
- pain management
- insulin resistance
- dna methylation
- adipose tissue
- squamous cell
- combination therapy
- breast cancer risk