Dose estimation for bivalirudin during pediatric cardiopulmonary bypass.
Philip WolstencroftPhilip ArnoldBrian Joseph AndersonPublished in: Paediatric anaesthesia (2021)
Bivalirudin infusion in children should be started after loading dose at rates greater than those used in adults. Dose in neonates remains uncertain because neither pharmacokinetics nor coagulation pharmacodynamics have been adequately characterized.