Takotsubo syndrome is a coronary microvascular disease: experimental evidence.
Feng DongLiya YinHamayak SisakianTatevik HakobyanLacey S JeongHirva JoshiEllianna HoffSelena ChandlerGeetika SrivastavaAbdur Rahman JabirKelly KimballYeong-Renn ChenChwen-Lih ChenPatrick T KangParisa ShabaniLindsay ShocklingThomas PucciKarlina KegecikChristopher KolzZhenyu JiaWilliam M ChilianVahagn OhanyanPublished in: European heart journal (2023)
Abnormalities in flow regulation between the LV apex and base cause TTS. When perfusion is normalized between the two regions, normal ventricular function is restored.