The role of adipogenic capacity and dysfunctional subcutaneous adipose tissue in the inheritance of type 2 diabetes mellitus: cross-sectional study.

Michaela ŠiklováVeronika ŠrámkováMichal KocEva KrauzováTerezie ČížkováBarbora OndrůjováMarek WilhelmZuzana VaraliováOndrej KudaJana NeubertLukáš LambertMoustafa ElkalafJan GojdaLenka Rossmeislová

Published in: Obesity (Silver Spring, Md.) (2024)

The intrinsic adipogenic potential of SAT is not affected by a family history of T2DM. However, alterations in LOX mRNA and polyunsaturated fatty acids in triacylglycerols are likely related to the risk of developing T2DM independent of obesity.

Keyphrases

adipose tissue
insulin resistance
glycemic control
metabolic syndrome
weight loss
high fat diet
type diabetes
high fat diet induced
mitochondrial dna
weight gain
skeletal muscle
binding protein
gene expression
dna methylation
body mass index
risk assessment