Treating hemolysis due to perivalvular leaks: It is all about modifying micro-jets and not the volume of regurgitation.
Ian C GilchristPublished in: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions (2020)
Paravalvular leak closure may have a therapeutic effect on the extent of hemolysis that some patients experience after valve surgery. Reduction of hemolysis is most likely in a patient with a mechanical valve and is not necessarily correlated with the volume of regurgitative flow or its subsequent reduction. Hemolysis associated with biological valves are less likely to respond to perivalvular leak closure suggesting that mechanisms other than net volume of regurgitation or micro-jets are present and should be considered.
Keyphrases
- aortic valve
- aortic stenosis
- ejection fraction
- transcatheter aortic valve replacement
- transcatheter aortic valve implantation
- aortic valve replacement
- red blood cell
- end stage renal disease
- mitral valve
- newly diagnosed
- chronic kidney disease
- minimally invasive
- case report
- prognostic factors
- coronary artery bypass
- left ventricular
- acute coronary syndrome
- patient reported outcomes
- atrial fibrillation