The adhesion and migration of microglia to β-amyloid (Aβ) is decreased with aging and inhibited by Nogo/NgR pathway.

Yinquan FangJianing WangLemeng YaoChenhui LiJing WangYuan LiuXia TaoHao SunHong Liao

Published in: Journal of neuroinflammation (2018)

Taken together, Nogo/NgR pathway could take part in Aβ pathology in AD by modulating microglial adhesion and migration to Aβ and the Nogo/NgR pathway might be an important target for treating AD.

Keyphrases

spinal cord injury
lipopolysaccharide induced
pseudomonas aeruginosa
cystic fibrosis