Characterizing the time course of cerebrovascular reactivity in multiple sclerosis.
John A LincolnKhader M HasanRefaat E GabrJerry S WolinskyPublished in: Journal of neuroimaging : official journal of the American Society of Neuroimaging (2022)
Our findings show a prolonged time course in vascular reactivity after ACZ stimulus in MS patients with a similar time course for both gray and white matter brain regions, including in previously injured tissue. Our preliminary results suggest that blood flow can be augmented in the established MS lesion suggesting that even previously injured tissue might be responsive to treatment.