Effect of Heme Oxygenase-1 on Melanoma Development in Mice-Role of Tumor-Infiltrating Immune Cells.

Halina WasTomasz CichonRyszard SmolarczykBozena LackowskaAgnieszka Irena Mazur-BiałyMagdalena MazurAgata SzadePawel DominikMilena MazanJerzy KotlinowskiAnna ZebzdaAnna KusienickaClaudine KiedaJozef DulakAlicja Jozkowicz

Published in: Antioxidants (Basel, Switzerland) (2020)

Although HO-1 overexpression in melanoma cells can enhance tumor progression in mice, its presence in host cells, including immune cells, can reduce growth and metastasis of melanoma.

Keyphrases

high fat diet induced
induced apoptosis
cell cycle arrest
cell proliferation
transcription factor
type diabetes
pi k akt
wild type
insulin resistance
oxidative stress
metabolic syndrome
adipose tissue
basal cell carcinoma
skeletal muscle