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Intracerebral Iron Accumulation may be Associated with Secondary Brain Injury in Patients with Poor Grade Subarachnoid Hemorrhage.

Raimund HelbokVerena RassMario KoflerHeribert TalaszAlois SchiefeckerMax GaaschChristoph ScherflerBettina PfauslerClaudius ThoméRonny BeerHerbert H LindnerErich Schmutzhard
Published in: Neurocritical care (2021)
This study suggests that iron accumulates in the cerebral white matter in patients with poor grade SAH. These findings may support trials aiming to scavenger brain extracellular iron based on the hypothesis that iron-mediated neurotoxicity may contribute to acute and secondary brain injury following SAH.
Keyphrases
  • brain injury
  • subarachnoid hemorrhage
  • cerebral ischemia
  • white matter
  • iron deficiency
  • resting state
  • drug induced