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Anti-CLL1-based CAR T-cells with 4-1-BB or CD28/CD27 stimulatory domains in treating childhood refractory/relapsed acute myeloid leukemia.

Kunlin PeiHaoyu XuPengfei WangWening GanZhengbin HuXiaoling SuHui ZhangYingyi He
Published in: Cancer medicine (2023)
A preliminary similar efficacy/safety index was observed in anti-CLL1-based CAR T-cells with 4-1BB or CD28/CD27 co-stimulatory elements in treating pediatric R/R-AML.
Keyphrases
  • acute myeloid leukemia
  • growth factor
  • allogeneic hematopoietic stem cell transplantation
  • chronic lymphocytic leukemia
  • acute lymphoblastic leukemia
  • early life
  • hodgkin lymphoma
  • childhood cancer