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Harmonization of brain PET images in multi-center PET studies using Hoffman phantom scan.

Mahnaz ShekariEline E VerwerMaqsood YaqubMarcel DaamenChristopher BuckleyGiovanni B FrisoniPieter Jelle VisserGill FarrarFrederik BarkhofJuan-Domingo GispertRonald Boellaardnull null
Published in: EJNMMI physics (2023)
Harmonizing the EIR of brain PET scans significantly reduced image quality variability while minimally affecting quantitative accuracy. This method can be used prospectively for harmonizing scans to target sharper resolutions and is robust against dose-calibrator errors. Comparable image quality is attainable in brain PET multi-center studies while maintaining quantitative accuracy.
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