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Association of outpatient ACE inhibitors and angiotensin receptor blockers and outcomes of acute respiratory illness: a retrospective cohort study.

Molly Moore JefferyNathan W CumminsTimothy M DempseyAndrew H LimperNilay D ShahFernanda Bellolio
Published in: BMJ open (2021)
Outpatient use of ARBs was associated with better outcomes with AVRI compared with other medications for HTN. ACEis were associated with reduced risk of death, but with minimal or no reduction in risk of other complications. A falsification analysis conducted to provide context on the possible causal implications of these findings did not provide a clear answer. Further analysis using observational data will benefit from additional approaches to assess causal relationships between these drugs and outcomes in AVRI.
Keyphrases
  • angiotensin converting enzyme
  • angiotensin ii
  • liver failure
  • type diabetes
  • machine learning
  • drug induced
  • adipose tissue
  • skeletal muscle
  • insulin resistance
  • data analysis
  • respiratory tract