Regulation of immune response genes in the skin of allergic and clinically tolerant individuals exposed to p-phenylenediamine.
Sanne S MeisserYasutaka MitamuraCan AltunbulakliJosefine BandierMorten S OpstrupAnne-Sofie Østergaard GadsbøllManru LiGe TanMübeccel AkdişMübeccel AkdisCarsten GeislerJeanne D JohansenCharlotte Menné BonefeldPublished in: Allergy (2024)
This study demonstrates that there are no true non-responders to PPD but that the immune response elicited by PPD differs between individuals and can lead to either tolerance, subclinical inflammation or allergy.