Individual Participant Data Network Meta-Analysis of Neoadjuvant Chemotherapy or Chemoradiotherapy in Esophageal or Gastroesophageal Junction Carcinoma.
Matthieu FaronMaurice Cheugoua-ZanetsieJayne TierneyPierre ThirionMatthew G NankivellKathryn WinterHong YangJoel ShapiroDewi VernereyB Mark SmithersThomas WalshGuillaume PiessenMagnus NilssonJurjen J BoonstraMarc YchouSimon LawDavid CunninghamFlorent de VathaireMichael StahlSusan UrbaMichele ValmasoniDanièle WilliaumeJanine ThomasFlorian LordickJoel E TepperJack RothVal GebskiBryan BurmeisterXavier PaolettiJohanna van SandickJianhua FuJean-Pierre PignonMichel DucreuxStefan Michielsnull nullPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Neoadjuvant chemotherapy and chemoradiotherapy were consistently better than S alone across histology, but with some variation in the magnitude of treatment effect by sex for CRS and tumor location for CS. A strong OS difference between CS and CRS was not identified.