LncRNA as a multifunctional regulator in cancer multi-drug resistance.
Jiaying HeShaomi ZhuXin LiangQinxiu ZhangXiaohong LuoChi LiuLinjiang SongPublished in: Molecular biology reports (2021)
LncRNAs closely participated in cancer drug resistance by regulating miRNA, signaling pathways, proteins, cancer stem cells, pro- and ant-apoptosis, and autophagy. lncRNAs can be used as biomarkers of the possible treatment target in chemotherapy, which could provide solutions to the problem of drug resistance in chemotherapy in the future.
Keyphrases
- papillary thyroid
- cancer stem cells
- signaling pathway
- endoplasmic reticulum stress
- oxidative stress
- cell death
- squamous cell
- locally advanced
- drug delivery
- lymph node metastasis
- long non coding rna
- induced apoptosis
- radiation therapy
- current status
- pi k akt
- cell proliferation
- cancer therapy
- anti inflammatory
- long noncoding rna
- combination therapy
- genome wide identification