Porphyromonas gingivalis exacerbates alcoholic liver disease by altering gut microbiota composition and host immune response in mice.

Yuting GaoPeng ZhangYiming WeiChaolin YeDaqing Mao Dasheng Xia Yi Luo

Published in: Journal of clinical periodontology (2023)

These results indicate that P. gingivalis accelerates the pathogenesis of ALD via the oral-gut-liver axis, necessitating a new treatment strategy for patients with ALD complicated by periodontitis.

Keyphrases

immune response
liver injury
type diabetes
high fat diet induced
combination therapy
metabolic syndrome
inflammatory response
drug induced