Restricted Mean Survival Time-Can It Be a New Tool in Assessing the Survival of Non-Small Cell Lung Cancer Patients Treated with Immune Checkpoint Inhibitors?
Cristina-Florina PîrlogRaluca Simona CostacheAndreea Ioana ParoșanuCristina Orlov SlavuMihaela OlaruAna Maria PopaCristian IaciuIrina NițăPompilia MoțatuHoria Teodor CotanAlexandru Vlad OprițaDaniel Octavian CostacheLoredana Cornelia Sabina ManolescuCornelia NițipirPublished in: Diagnostics (Basel, Switzerland) (2023)
The RMST is a new tool that helps researchers to better address the survival in studies with ICIs treatment where the PH fails, and the long-rank test is less efficient due to the existence of the long-term responses and delayed treatment effects. Patients with irAEs have a better prognosis than those without irAEs in the first-line settings. The ECOG performance status and the number of organs affected by metastasis must be considered when selecting patients for ICIs treatment.