Glycerol content within the WHO ethanol-based handrub formulation: balancing tolerability with antimicrobial efficacy.

Mayra Gonçalves MeneguetiAna Maria LausMárcia Aparecida CiolMaria Auxiliadora-MartinsAnibal Basile-FilhoElucir GirDaniela PiresDidier PittetFernando Bellissimo-Rodrigues

Published in: Antimicrobial resistance and infection control (2019)

In a tropical climate setting, the WHO-modified EBHR formulation containing 0.5% glycerol led to better ratings of skin tolerance than the original formulation, and, therefore, may offer the best balance between skin tolerance and antimicrobial efficacy.

Keyphrases

drug delivery
climate change
staphylococcus aureus
soft tissue
wound healing
open label
clinical trial