Analysis of ceRNA network of differentially expressed genes in FaDu cell line and a cisplatin-resistant line derived from it.
Gehou ZhangGuolin TanTieqi LiJingang AiYexun SongZheng ZhouJian XiaoWei LiPublished in: PeerJ (2021)
The microarray helped to find DEGs in cisplatin-resistant hypopharyngeal cancer. TNF, IL-17 and JAK-STAT signaling pathways might be more significant for cisplatin-resistance. MiR-197-5p, miR-6808-5p, APOE, MMP1, S100A9 and CYP24A1 might be potential genes inducing resistance.
Keyphrases
- bioinformatics analysis
- genome wide
- signaling pathway
- rheumatoid arthritis
- papillary thyroid
- long non coding rna
- high fat diet
- type diabetes
- epithelial mesenchymal transition
- squamous cell
- genome wide analysis
- adipose tissue
- gene expression
- cell proliferation
- lymph node metastasis
- young adults
- transcription factor
- climate change
- insulin resistance
- oxidative stress
- network analysis