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Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study.

Alice Rose CarterDipender GillNeil M DaviesAmy E TaylorTaavi TillmannJulien VaucherRobyn E WoottonMarcus R MunafòGibran HemaniRainer MalikSudha SeshadriDaniel WooStephen BurgessGeorge Davey SmithMichael V HolmesIoanna TzoulakiLaura D HoweAbbas Dehghan
Published in: BMJ (Clinical research ed.) (2019)
BMI, systolic blood pressure, and smoking behaviour mediate a substantial proportion of the protective effect of education on the risk of cardiovascular outcomes and intervening on these would lead to reductions in cases of cardiovascular disease attributable to lower levels of education. However, more than half of the protective effect of education remains unexplained and requires further investigation.
Keyphrases
  • cardiovascular disease
  • blood pressure
  • healthcare
  • quality improvement
  • heart failure
  • smoking cessation
  • adipose tissue
  • heart rate
  • physical activity
  • coronary artery disease
  • cardiovascular events
  • blood glucose