Overexpression of lncRNAs with endogenous lengths and functions using a lncRNA delivery system based on transposon.

Yin ZhangYong-Xin HuangXin JinJie ChenLi PengDan-Lan WangYun LiXin-Yi YaoJian-You LiaoJie-Hua HeKaiShun HuDaning LuYabin GuoDong Yin

Published in: Journal of nanobiotechnology (2021)

Our study demonstrated that improper transcriptional termination from lentiviral vectors have fundamental effects on molecular action and cellular function of lncRNAs. The ELECTS system developed in this study will provide a convenient and reliable method for the lncRNA study.

Keyphrases

gene expression
transcription factor
cell proliferation
heat shock