The Influence of Body Mass Index on Growth Factor Composition in the Platelet-Rich Plasma in Patients with Knee Osteoarthritis.

Michał WicińskiDawid SzwedowskiŁukasz WróbelSławomir JekaJan Zabrzyński

Published in: International journal of environmental research and public health (2022)

BMI does not influence the level of selected growth factors in patients with knee osteoarthritis. Obese and non-obese patients had similar compositions of PDGF, TGF-β, EGF, FGF-2, IGF-1, and VEGF. PRP can be used in both groups with similar effects associated with growth factors' influence on articular cartilage.

Keyphrases

knee osteoarthritis
growth factor
obese patients
platelet rich plasma
body mass index
bariatric surgery
gastric bypass
weight loss
weight gain
metabolic syndrome
roux en y gastric bypass
type diabetes
physical activity
endothelial cells
transforming growth factor
vascular smooth muscle cells
binding protein