Huangkui Lianchang Decoction Ameliorates DSS-Induced Ulcerative Colitis in Mice by Inhibiting the NF-kappaB Signaling Pathway.
Zhong-Qi HeQing ZhouKe WenBen-Sheng WuXueliang SunXiao-Peng WangYu-Gen ChenPublished in: Evidence-based complementary and alternative medicine : eCAM (2019)
HLD can alleviate the inflammation caused by ulcerative colitis. In particular, high doses of HLD can significantly alleviate intestinal inflammation and have comparable efficacy to Mesalazine. We propose that the anti-inflammatory activity of HLD on DSS-induced colitis in mice may involve the inhibition of the NF-κB pathway.
Keyphrases
- signaling pathway
- ulcerative colitis
- oxidative stress
- pi k akt
- high fat diet induced
- diabetic rats
- induced apoptosis
- epithelial mesenchymal transition
- lps induced
- nuclear factor
- type diabetes
- drug induced
- inflammatory response
- cell proliferation
- adipose tissue
- insulin resistance
- wild type
- endothelial cells
- toll like receptor
- endoplasmic reticulum stress
- stress induced