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Development of a cortical delay discounting assay: a potential biomarker of externalizing disorders.

Naomi SadehRickie MiglinNadia BounouaAna SheehanJeffrey M Spielberg
Published in: Psychological medicine (2021)
Across three studies, a cortical assay of impulsive choice evidenced consistent associations with drug use and delay discounting task performance. It was also uniquely associated with psychiatric disorders that share impulsivity as a core feature. Together, findings support the utility of C-DD as a neurobiological assay of impulsive decision-making and a possible biomarker of externalizing disorders.
Keyphrases
  • high throughput
  • decision making
  • machine learning
  • single cell
  • case control