A Novel Nanostructured Surface on Titanium Implants Increases Osseointegration in a Sheep Model.

Claire Frances Jones Ryan David Quarrington Helen Tsangari Yolandi StarczakAdnan MulaibrahimovicAnouck L S Burzava Chris Christou Alex J BarkerJames MorelRichard BrightDan BarkerToby BrownKrasimir A Vasilev Paul H Anderson

Published in: Clinical orthopaedics and related research (2022)

Given that the AHT implants formed a more robust interface with cortical and cancellous bone than the PCHA implants, a clinical noninferiority study using hip stems with identical geometries can now be performed to compare the same surfaces used in this study. The results of this preclinical study provide an ethical baseline to proceed with such a clinical study given the potential of the alkaline heat-treated surface to reduce periprosthetic joint infection and enhance implant osseointegration.

Keyphrases

soft tissue
escherichia coli
staphylococcus aureus
pseudomonas aeruginosa
climate change
total knee arthroplasty
total hip
decision making