Effects of Oral ALZ-801/Valiltramiprosate on Plasma Biomarkers, Brain Hippocampal Volume, and Cognition: Results of 2-Year Single-Arm, Open-Label, Phase 2 Trial in APOE4 Carriers with Early Alzheimer's Disease.

John A HeySusan AbushakraKaj BlennowEric M ReimanJakub HortNiels D PrinsKaterina SheardovaPatrick KesslakLarry ShenXinyi ZhuAdem AlbayrakJijo PaulJean F SchaeferAidan PowerMartin Tolar

Published in: Drugs (2024)

https://clinicaltrials.gov/study/NCT04693520 .

Keyphrases

open label
cognitive decline
white matter
clinical trial
mild cognitive impairment
cerebral ischemia
high fat diet
type diabetes
adipose tissue
metabolic syndrome
multiple sclerosis
radiation therapy
phase ii study
phase iii
insulin resistance