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FAP deficiency enhances thermogenesis and attenuates metabolic inflammation in diet-induced obesity.

Yunyun WuYun LiMiao SunFangliu YuHui LiuJingyun XuXingli Tang
Published in: Obesity (Silver Spring, Md.) (2023)
This study demonstrated that FAP deficiency protects mice against diet-induced obesity and related metabolic dysfunction. Furthermore, the protective effects are probably mediated via the promotion of WAT beiging and suppression of inflammation.
Keyphrases
  • high fat diet induced
  • oxidative stress
  • insulin resistance
  • metabolic syndrome
  • weight loss
  • adipose tissue
  • type diabetes
  • weight gain
  • skeletal muscle
  • body mass index
  • smoking cessation
  • drug induced