High-content image screening to identify chemical modulators for peroxisome and ferroptosis.

Daheng ZhengFei LiShanshan WangPu-Ste LiuXin Xie

Published in: Cellular & molecular biology letters (2024)

Our findings pinpoint novel cellular targets that might be involved in peroxisome homeostasis and indicate that compounds promoting peroxisomal abundance could be jointly applied with ferroptosis inducers to potentiate anticancer effect.

Keyphrases

cell death
small molecule
deep learning
antibiotic resistance genes
machine learning
wastewater treatment