Secreted factors from dental pulp stem cells improve Sjögren's syndrome via regulatory T cell-mediated immunosuppression.

Mayu Matsumura-KawashimaKenichi OgataMasafumi MoriyamaYuka MurakamiTatsuya KawadoSeiji Nakamura

Published in: Stem cell research & therapy (2021)

These results indicated that DPSC-CM ameliorated SS by promoting Treg cell differentiation and inhibiting Th17 cell differentiation in the mouse spleen.

Keyphrases

stem cells
signaling pathway
transcription factor
case report
cell therapy
mesenchymal stem cells