Altered glucagon and GLP-1 responses to oral glucose in children and adolescents with obesity and insulin resistance.
Sara Elizabeth StinsonIerai Fernández de Retana AlzolaEmilie Damgaard Brünner HovendalMorten Asp Vonsild LundCilius Esmann FonvigLouise Aas HolmAnna Elisabet JonssonChristine Frithioff-BøjsøeMichael ChristiansenOluf PedersenLars ÄngquistThorkild I A SørensenJens Juul HolstBolette HartmannJens-Christian HolmTorben HansenPublished in: The Journal of clinical endocrinology and metabolism (2023)
The OIR-group had elevated fasting concentrations of glucagon and GLP-1, and higher glucagon, but lower GLP-1 responses during an OGTT compared to the OIS- and NW-groups. In contrast, the OIS-group had similar hormone responses to the NW-group.