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Association of PON1, TNF-α and TGF-β gene polymorphisms with prognosis in oral and oropharyngeal squamous cell carcinoma.

Ingrede Tatiane Serafim SantanaJosé Nilson Andrade Dos SantosVinicius Lima de AlmeidaWaldhenice Nunes Silveira FerreiraEdilmar Moura SantosRoseana de Almeida FreitasClaudia Cristina Kaiser PintoIkaro Daniel de Carvalho BarretoFelipe Rodrigues de Matos
Published in: Acta odontologica Scandinavica (2021)
Results suggest that the rs1800629 and rs1800469 could exert influence in the more aggressive behaviour of OOSCC and the genotypes AG of rs1800629, and TT of rs662 could be markers with prognostic value in OOSCC.
Keyphrases
  • squamous cell carcinoma
  • transforming growth factor
  • radiation therapy
  • signaling pathway
  • epithelial mesenchymal transition