Influence of food on the gastric motor effect of the Kampo medicine rikkunshito in rat.
M NahataY MizuharaC SadakaneJ WatanabeN FujitsukaTomohisa HattoriPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2017)
We show that the pharmacological action of rikkunshito is influenced by food in rats. The efficacy of rikkunshito may be associated with decreased absorption of its active ingredient atractylodin when food is in the stomach.