RBM10-TFE3 renal cell carcinoma characterised by paracentric inversion with consistent closely split signals in break-apart fluorescence in-situ hybridisation: study of 10 cases and a literature review.
Ikuma KatoMitsuko FuruyaMasaya BabaYoichi KamedaMasanori YasudaKoshiro NishimotoMasafumi OyamaToshinari YamasakiOsamu OgawaHitoshi NiinoNoboru NakaigawaYuta YanoKazumasa SakamotoYoji UrataKazuya MikamiShigetaka YamasakiReiko TanakaToshio TakagiTsunenori KondoYoji NagashimaPublished in: Histopathology (2019)
The present study suggests that the carcinogenesis of RBM10-TFE3 RCC in some, but not all, patients may be associated with chronic kidney disease. The aggressive nature of RBM10-TFE3 RCC should be considered, as five patients experienced metastases.