Effect of poor glycaemic control on plasma levels and activity of protein C, protein S, and antithrombin III in type 2 diabetes mellitus.

Otchere Addai-MensahMax Efui Annani-AkollorFrederick Obeng NsafoahLinda Ahenkorah FondjoEddie-Williams OwireduKwabena Owusu DanquahRichard Vikpebah DuneehFrancis Agyei Amponsah

Published in: PloS one (2019)

Poorly-managed type 2 diabetes mellitus is associated with reduced levels and activity of PC, PS and AT III compared to well-managed T2DM. Though use of statins may improve the levels and activity of the PC, PS and AT III in T2DM, their effect is limited in the presence of poorly-controlled T2DM. Proper management of diabetes is essential to reduce the likelihood of thrombotic events among T2DM patients.

Keyphrases

glycemic control
type diabetes
cardiovascular disease
end stage renal disease
chronic kidney disease
ejection fraction
amino acid
prognostic factors
binding protein
patient reported outcomes
patient reported